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Tacrolimus Trough and Dose Intra-Patient Variability and CYP3A5 Genotype: Effects on Acute Rejection and Graft Failure in European American and African American Kidney Transplant Recipients
BACKGROUND: Suboptimal immunosuppression after kidney transplantation contributes to toxicity and loss of efficacy. Little is known regarding the impact of intra-patient variability of tacrolimus (TAC) doses and troughs in the early post-transplant period or the influence of genetic variants on vari...
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| Publicado no: | Clin Transplant |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6317347/ https://ncbi.nlm.nih.gov/pubmed/30318646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ctr.13424 |
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