Attempted validation of 44 reported SNPs associated with tacrolimus troughs in a cohort of kidney allograft recipients

AIM: Multiple genetic variants have been associated with variation in tacrolimus (TAC) trough concentrations. Unfortunately, additional studies do not confirm these associations, leading one to question if a reported association is accurate and reliable. We attempted to validate 44 published variant...

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Bibliographic Details
Published in:Pharmacogenomics
Main Authors: Oetting, William S, Wu, Baolin, Schladt, David P, Guan, Weihua, Remmel, Rory P, Dorr, Casey, Mannon, Roslyn B, Matas, Arthur J, Israni, Ajay K, Jacobson, Pamala A
Format: Artigo
Language:Inglês
Published: Future Medicine Ltd 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021962/
https://ncbi.nlm.nih.gov/pubmed/29318894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2017-0187
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