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The genotype‐phenotype landscape of an allosteric protein

Allostery is a fundamental biophysical mechanism that underlies cellular sensing, signaling, and metabolism. Yet a quantitative understanding of allosteric genotype‐phenotype relationships remains elusive. Here, we report the large‐scale measurement of the genotype‐phenotype landscape for an alloste...

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Détails bibliographiques
Publié dans:Mol Syst Biol
Auteurs principaux: Tack, Drew S, Tonner, Peter D, Pressman, Abe, Olson, Nathan D, Levy, Sasha F, Romantseva, Eugenia F, Alperovich, Nina, Vasilyeva, Olga, Ross, David
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009258/
https://ncbi.nlm.nih.gov/pubmed/33784029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.202010179
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