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Genotype to Phenotype Mapping and the Fitness Landscape of the E. coli lac Promoter
Genotype-to-phenotype maps and the related fitness landscapes that include epistatic interactions are difficult to measure because of their high dimensional structure. Here we construct such a map using the recently collected corpora of high-throughput sequence data from the 75 base pairs long mutag...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Public Library of Science
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3641078/ https://ncbi.nlm.nih.gov/pubmed/23650500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061570 |
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