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Human ancient DNA analyses reveal the high burden of tuberculosis in Europeans over the last 2,000 years

Tuberculosis (TB), usually caused by Mycobacterium tuberculosis bacteria, is the first cause of death from an infectious disease at the worldwide scale, yet the mode and tempo of TB pressure on humans remain unknown. The recent discovery that homozygotes for the P1104A polymorphism of TYK2 are at hi...

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Publicat a:Am J Hum Genet
Autors principals: Kerner, Gaspard, Laval, Guillaume, Patin, Etienne, Boisson-Dupuis, Stéphanie, Abel, Laurent, Casanova, Jean-Laurent, Quintana-Murci, Lluis
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008489/
https://ncbi.nlm.nih.gov/pubmed/33667394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2021.02.009
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