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Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes

Human genes governing innate immunity provide a valuable tool for the study of the selective pressure imposed by microorganisms on host genomes. A comprehensive, genome-wide study of how selective constraints and adaptations have driven the evolution of innate immunity genes is missing. Using full-g...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Deschamps, Matthieu, Laval, Guillaume, Fagny, Maud, Itan, Yuval, Abel, Laurent, Casanova, Jean-Laurent, Patin, Etienne, Quintana-Murci, Lluis
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716683/
https://ncbi.nlm.nih.gov/pubmed/26748513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.11.014
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