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Tumor Hypoxia Drives Genomic Instability

Cancer is a leading cause of death worldwide. As a common characteristic of cancer, hypoxia is associated with poor prognosis due to enhanced tumor malignancy and therapeutic resistance. The enhanced tumor aggressiveness stems at least partially from hypoxia-induced genomic instability. Therefore, a...

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Publicat a:Front Cell Dev Biol
Autors principals: Tang, Ming, Bolderson, Emma, O’Byrne, Kenneth J., Richard, Derek J.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007910/
https://ncbi.nlm.nih.gov/pubmed/33796526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.626229
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