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PARP Inhibitors: Clinical Relevance, Mechanisms of Action and Tumor Resistance
The Poly (ADP-ribose) polymerase (PARP) family has many essential functions in cellular processes, including the regulation of transcription, apoptosis and the DNA damage response. PARP1 possesses Poly (ADP-ribose) activity and when activated by DNA damage, adds branched PAR chains to facilitate the...
Tallennettuna:
| Julkaisussa: | Front Cell Dev Biol |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Frontiers Media S.A.
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7509090/ https://ncbi.nlm.nih.gov/pubmed/33015058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.564601 |
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