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Expanding the scope of plant genome engineering with Cas12a orthologs and highly multiplexable editing systems
CRISPR-Cas12a is a promising genome editing system for targeting AT-rich genomic regions. Comprehensive genome engineering requires simultaneous targeting of multiple genes at defined locations. Here, to expand the targeting scope of Cas12a, we screen nine Cas12a orthologs that have not been demonst...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , , , , , , , , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8007695/ https://ncbi.nlm.nih.gov/pubmed/33782402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22330-w |
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