Expanding the scope of plant genome engineering with Cas12a orthologs and highly multiplexable editing systems

CRISPR-Cas12a is a promising genome editing system for targeting AT-rich genomic regions. Comprehensive genome engineering requires simultaneous targeting of multiple genes at defined locations. Here, to expand the targeting scope of Cas12a, we screen nine Cas12a orthologs that have not been demonst...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Zhang, Yingxiao, Ren, Qiurong, Tang, Xu, Liu, Shishi, Malzahn, Aimee A., Zhou, Jianping, Wang, Jiaheng, Yin, Desuo, Pan, Changtian, Yuan, Mingzhu, Huang, Lan, Yang, Han, Zhao, Yuxin, Fang, Qing, Zheng, Xuelian, Tian, Li, Cheng, Yanhao, Le, Ysa, McCoy, Bailey, Franklin, Lidiya, Selengut, Jeremy D., Mount, Stephen M., Que, Qiudeng, Zhang, Yong, Qi, Yiping
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007695/
https://ncbi.nlm.nih.gov/pubmed/33782402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22330-w
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg