Application of CRISPR-Cas12a temperature sensitivity for improved genome editing in rice, maize, and Arabidopsis

BACKGROUND: CRISPR-Cas12a (formerly Cpf1) is an RNA-guided endonuclease with distinct features that have expanded genome editing capabilities. Cas12a-mediated genome editing is temperature sensitive in plants, but a lack of a comprehensive understanding on Cas12a temperature sensitivity in plant cel...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Malzahn, Aimee A., Tang, Xu, Lee, Keunsub, Ren, Qiurong, Sretenovic, Simon, Zhang, Yingxiao, Chen, Hongqiao, Kang, Minjeong, Bao, Yu, Zheng, Xuelian, Deng, Kejun, Zhang, Tao, Salcedo, Valeria, Wang, Kan, Zhang, Yong, Qi, Yiping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357469/
https://ncbi.nlm.nih.gov/pubmed/30704461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-019-0629-5
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