Application of CRISPR-Cas12a temperature sensitivity for improved genome editing in rice, maize, and Arabidopsis

BACKGROUND: CRISPR-Cas12a (formerly Cpf1) is an RNA-guided endonuclease with distinct features that have expanded genome editing capabilities. Cas12a-mediated genome editing is temperature sensitive in plants, but a lack of a comprehensive understanding on Cas12a temperature sensitivity in plant cel...

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Bibliografiske detaljer
Udgivet i:BMC Biol
Main Authors: Malzahn, Aimee A., Tang, Xu, Lee, Keunsub, Ren, Qiurong, Sretenovic, Simon, Zhang, Yingxiao, Chen, Hongqiao, Kang, Minjeong, Bao, Yu, Zheng, Xuelian, Deng, Kejun, Zhang, Tao, Salcedo, Valeria, Wang, Kan, Zhang, Yong, Qi, Yiping
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357469/
https://ncbi.nlm.nih.gov/pubmed/30704461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-019-0629-5
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