Viral infection modulates Qa-1(b) in infected and bystander cells to properly direct NK cell killing

Natural killer (NK) cell activation depends on the signaling balance of activating and inhibitory receptors. CD94 forms inhibitory receptors with NKG2A and activating receptors with NKG2E or NKG2C. We previously demonstrated that CD94-NKG2 on NK cells and its ligand Qa-1(b) are important for the res...

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Vydáno v:J Exp Med
Hlavní autoři: Ferez, Maria, Knudson, Cory J., Lev, Avital, Wong, Eric B., Alves-Peixoto, Pedro, Tang, Lingjuan, Stotesbury, Colby, Sigal, Luis J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006856/
https://ncbi.nlm.nih.gov/pubmed/33765134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201782
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