Viral infection modulates Qa-1(b) in infected and bystander cells to properly direct NK cell killing

Natural killer (NK) cell activation depends on the signaling balance of activating and inhibitory receptors. CD94 forms inhibitory receptors with NKG2A and activating receptors with NKG2E or NKG2C. We previously demonstrated that CD94-NKG2 on NK cells and its ligand Qa-1(b) are important for the res...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Ferez, Maria, Knudson, Cory J., Lev, Avital, Wong, Eric B., Alves-Peixoto, Pedro, Tang, Lingjuan, Stotesbury, Colby, Sigal, Luis J.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006856/
https://ncbi.nlm.nih.gov/pubmed/33765134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201782
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