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α2β1 integrin is required for optimal NK cell proliferation during viral infection but not for acquisition of effector functions or NK cell-mediated virus control

Natural killer (NK) cells play an important role in antiviral resistance. The integrin α2 (α2), which dimerizes with integrin β1 (β1), distinguishes NK cells from Innate Lymphoid Cells 1 (ILC1) and other leukocytes. Despite its use as an NK cell marker, little is known about the role of α2β1 in NK c...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Immunol
Main Authors: Stotesbury, Colby, Alves-Peixoto, Pedro, Montoya, Brian, Ferez, Maria, Nair, Savita, Snyder, Christopher M., Zhang, Shunchuan, Knudson, Cory J., Sigal, Luis J.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065959/
https://ncbi.nlm.nih.gov/pubmed/32015010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900927
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