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Genetic background influences LRRK2-mediated Rab phosphorylation in the rat brain
Pathogenic missense mutations in the leucine-rich repeat kinase 2 gene, encoding LRRK2, results in the upregulation of Rab10 and Rab12 phosphorylation in different cells and tissues. Here, we evaluate levels of the LRRK2 kinase substrates pT73-Rab10 and pS106-Rab12 proteins in rat brain tissues from...
Shranjeno v:
| izdano v: | Brain Res |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8006086/ https://ncbi.nlm.nih.gov/pubmed/33600829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2021.147372 |
| Oznake: |
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