Llwytho...

Genetic background influences LRRK2-mediated Rab phosphorylation in the rat brain

Pathogenic missense mutations in the leucine-rich repeat kinase 2 gene, encoding LRRK2, results in the upregulation of Rab10 and Rab12 phosphorylation in different cells and tissues. Here, we evaluate levels of the LRRK2 kinase substrates pT73-Rab10 and pS106-Rab12 proteins in rat brain tissues from...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Brain Res
Prif Awduron: Kelly, Kaela, Chang, Allison, Hastings, Lyndsay, Abdelmotilib, Hisham, West, Andrew B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006086/
https://ncbi.nlm.nih.gov/pubmed/33600829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2021.147372
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