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Aldose reductase deficiency inhibits LPS-induced M1 response in macrophages by activating autophagy
Macrophage M1 polarization mediates inflammatory responses and tissue damage. Recently, aldose reductase (AR) has been shown to play a critical role in M1 polarization in macrophages. However, the underlying mechanisms are unknown. Here, we demonstrated, for the first time, that AR deficiency repres...
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| Publicado no: | Cell Biosci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8004403/ https://ncbi.nlm.nih.gov/pubmed/33771228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-021-00576-7 |
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