Germline Variation in PDCD1 Is Associated with Overall Survival in Patients with Metastatic Melanoma Treated with Anti-PD-1 Monotherapy

SIMPLE SUMMARY: Although the introduction of programmed cell death 1 (PD-1) immune checkpoint inhibitors (ICIs) has significantly improved the overall survival (OS) in patients with metastatic melanoma, a substantial number of patients do not benefit from ICIs. Therefore, the predictive value of sin...

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Bibliografske podrobnosti
izdano v:Cancers (Basel)
Main Authors: de With, Mirjam, Hurkmans, Daan P., Oomen-de Hoop, Esther, Lalouti, Ayoub, Bins, Sander, El Bouazzaoui, Samira, van Brakel, Mandy, Debets, Reno, Aerts, Joachim G. J. V., van Schaik, Ron H. N., Mathijssen, Ron H. J., van der Veldt, Astrid A. M.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002987/
https://ncbi.nlm.nih.gov/pubmed/33803602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061370
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