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Exons and introns exhibit transcriptional strand asymmetry of dinucleotide distribution, damage formation and DNA repair
Recent cancer sequencing efforts have uncovered asymmetry in DNA damage induced mutagenesis between the transcribed and non-transcribed strands of genes. Here, we investigate the major type of damage induced by ultraviolet (UV) radiation, the cyclobutane pyrimidine dimers (CPDs), which are formed pr...
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| Pubblicato in: | NAR Genom Bioinform |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8002178/ https://ncbi.nlm.nih.gov/pubmed/33817640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqab020 |
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