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Exons and introns exhibit transcriptional strand asymmetry of dinucleotide distribution, damage formation and DNA repair

Recent cancer sequencing efforts have uncovered asymmetry in DNA damage induced mutagenesis between the transcribed and non-transcribed strands of genes. Here, we investigate the major type of damage induced by ultraviolet (UV) radiation, the cyclobutane pyrimidine dimers (CPDs), which are formed pr...

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Detalhes bibliográficos
Publicado no:NAR Genom Bioinform
Main Authors: Heilbrun, Elisheva E, Merav, May, Adar, Sheera
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002178/
https://ncbi.nlm.nih.gov/pubmed/33817640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqab020
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