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Exons and introns exhibit transcriptional strand asymmetry of dinucleotide distribution, damage formation and DNA repair

Recent cancer sequencing efforts have uncovered asymmetry in DNA damage induced mutagenesis between the transcribed and non-transcribed strands of genes. Here, we investigate the major type of damage induced by ultraviolet (UV) radiation, the cyclobutane pyrimidine dimers (CPDs), which are formed pr...

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Bibliografiska uppgifter
I publikationen:NAR Genom Bioinform
Huvudupphovsmän: Heilbrun, Elisheva E, Merav, May, Adar, Sheera
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002178/
https://ncbi.nlm.nih.gov/pubmed/33817640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqab020
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