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Discovery and Optimization of Selective Inhibitors of Meprin α (Part I)
Meprin α and β are zinc-dependent proteinases implicated in multiple diseases including cancers, fibrosis, and Alzheimer’s. However, until recently, only a few inhibitors of either meprin were reported and no inhibitors are in preclinical development. Moreover, inhibitors of other metzincins develop...
Gardado en:
| Publicado en: | Pharmaceuticals (Basel) |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8000592/ https://ncbi.nlm.nih.gov/pubmed/33671080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14030203 |
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