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Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function
Inflammasomes sense a number of pathogen and host damage signals to initiate a signaling cascade that triggers inflammatory cell death, termed pyroptosis. The inflammatory caspases (1/4/5/11) are the key effectors of this process through cleavage and activation of the pore-forming protein gasdermin...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8000503/ https://ncbi.nlm.nih.gov/pubmed/33723046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2018024118 |
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