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Targeting the Hypoxic and Acidic Tumor Microenvironment with pH-Sensitive Peptides

The delivery of cancer therapeutics can be limited by pharmacological issues such as poor bioavailability and high toxicity to healthy tissue. pH-low insertion peptides (pHLIPs) represent a promising tool to overcome these limitations. pHLIPs allow for the selective delivery of agents to tumors on t...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Dharmaratne, Nayanthara U., Kaplan, Alanna R., Glazer, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000199/
https://ncbi.nlm.nih.gov/pubmed/33806273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10030541
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