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pH-sensitive oncolytic adenovirus hybrid targeting acidic tumor microenvironment and angiogenesis
Although oncolytic adenoviruses (Ads) are an attractive option for cancer gene therapy, the intravenous administration of naked Ad still encounters unfavorable host responses, non-specific interactions, and heterogeneity in targeted cancer cells. To overcome these obstacles and achieve specific targ...
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| Publicado no: | J Control Release |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4419830/ https://ncbi.nlm.nih.gov/pubmed/25575865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.01.005 |
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