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pH-sensitive oncolytic adenovirus hybrid targeting acidic tumor microenvironment and angiogenesis
Although oncolytic adenoviruses (Ads) are an attractive option for cancer gene therapy, the intravenous administration of naked Ad still encounters unfavorable host responses, non-specific interactions, and heterogeneity in targeted cancer cells. To overcome these obstacles and achieve specific targ...
Gardado en:
| Publicado en: | J Control Release |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4419830/ https://ncbi.nlm.nih.gov/pubmed/25575865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.01.005 |
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