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pH-sensitive oncolytic adenovirus hybrid targeting acidic tumor microenvironment and angiogenesis

Although oncolytic adenoviruses (Ads) are an attractive option for cancer gene therapy, the intravenous administration of naked Ad still encounters unfavorable host responses, non-specific interactions, and heterogeneity in targeted cancer cells. To overcome these obstacles and achieve specific targ...

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Podrobná bibliografie
Vydáno v:J Control Release
Hlavní autoři: Choi, Joung-Woo, Jung, Soo-Jung, Kasala, Dayananda, Hwang, June Kyu, Hu, Jun, Bae, You Han, Yun, Chae-Ok
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419830/
https://ncbi.nlm.nih.gov/pubmed/25575865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.01.005
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