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Polymeric oncolytic adenovirus for cancer gene therapy

Oncolytic adenovirus (Ad) vectors present a promising modality to treat cancer. Many clinical trials have been done with either naked oncolytic Ad or combination with chemotherapies. However, the systemic injection of oncolytic Ad in clinical applications is restricted due to significant liver toxic...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Choi, Joung-Woo, Lee, Young Sook, Yun, Chae-Ok, Kim, Sung Wan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668934/
https://ncbi.nlm.nih.gov/pubmed/26453806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.10.009
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