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Human relaxin gene expression delivered by bioreducible dendrimer polymer for post-infarct cardiac remodeling in rats

In consensus, myocardial infarction (MI) is defined as irreversible cell death secondary to prolonged ischemia in heart. The aim of our study was to evaluate the therapeutic potential of anti-fibrotic human Relaxin-expressing plasmid DNA with hypoxia response element (HRE) 12 copies (HR1) delivered...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Lee, Young Sook, Choi, Joung-Woo, Oh, Jung-Eun, Yun, Chae-Ok, Kim, Sung Wan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448559/
https://ncbi.nlm.nih.gov/pubmed/27174688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.04.025
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