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Human relaxin gene expression delivered by bioreducible dendrimer polymer for post-infarct cardiac remodeling in rats
In consensus, myocardial infarction (MI) is defined as irreversible cell death secondary to prolonged ischemia in heart. The aim of our study was to evaluate the therapeutic potential of anti-fibrotic human Relaxin-expressing plasmid DNA with hypoxia response element (HRE) 12 copies (HR1) delivered...
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| Publicado en: | Biomaterials |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5448559/ https://ncbi.nlm.nih.gov/pubmed/27174688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.04.025 |
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