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Linearized oncolytic adenoviral plasmid DNA delivered by bioreducible polymers
As an effort to overcome limits of adenovirus (Ad) as a systemic delivery vector for cancer therapy, we developed a novel system using oncolytic Ad plasmid DNA with two bioreducible polymers: arginine-grafted bioreducible poly(disulfide amine)polymer (ABP) and PEG5k-conjugated ABP (ABP5k) in expecta...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319244/ https://ncbi.nlm.nih.gov/pubmed/22207073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.12.008 |
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