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Linearized oncolytic adenoviral plasmid DNA delivered by bioreducible polymers

As an effort to overcome limits of adenovirus (Ad) as a systemic delivery vector for cancer therapy, we developed a novel system using oncolytic Ad plasmid DNA with two bioreducible polymers: arginine-grafted bioreducible poly(disulfide amine)polymer (ABP) and PEG5k-conjugated ABP (ABP5k) in expecta...

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Hlavní autoři: Kim, Jaesung, Kim, Pyung-Hwan, Nam, Hye Yeong, Lee, Jung-Sun, Yun, Chae-Ok, Kim, Sung Wan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319244/
https://ncbi.nlm.nih.gov/pubmed/22207073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.12.008
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