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Hepatoma targeting peptide conjugated bio-reducible polymer complexed with oncolytic adenovirus for cancer gene therapy

Despite adenovirus (Ad) vector’s numerous advantages for cancer gene therapy, such as high ability of endosomal escape, efficient nuclear entry mechanism, and high transduction, and therapeutic efficacy, tumor specific targeting and antiviral immune response still remain as a critical challenge in c...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Choi, Joung-Woo, Kim, Hyun Ah, Nam, Kihoon, Na, Youjin, Yun, Chae-Ok, Kim, SungWan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688183/
https://ncbi.nlm.nih.gov/pubmed/26437261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.09.068
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