Protective Effect of Nasal Colonisation with ∆cps/piaA and ∆cps/proABC Streptococcus pneumoniae Strains against Recolonisation and Invasive Infection

Rationale: Nasopharyngeal administration of live virulence-attenuated Streptococcus pneumoniae strains is a potential novel preventative strategy. One target for creating reduced virulence S. pneumoniae strains is the capsule, but loss of the capsule reduces the duration of S. pneumoniae colonisatio...

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Vydáno v:Vaccines (Basel)
Hlavní autoři: Ramos-Sevillano, Elisa, Ercoli, Giuseppe, Guerra-Assunção, José Afonso, Felgner, Philip, Ramiro de Assis, Rafael, Nakajima, Rie, Goldblatt, David, Tetteh, Kevin Kweku Adjei, Heyderman, Robert Simon, Gordon, Stephen Brian, Ferreria, Daniela Mulari, Brown, Jeremy Stuart
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000150/
https://ncbi.nlm.nih.gov/pubmed/33804077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines9030261
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