The Influence of B Cell Depletion Therapy on Naturally Acquired Immunity to Streptococcus pneumoniae

The anti-CD20 antibody Rituximab to deplete CD20+ B cells is an effective treatment for rheumatoid arthritis and B cell malignancies, but is associated with an increased incidence of respiratory infections. Using mouse models we have investigated the consequences of B cell depletion on natural and a...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Ercoli, Giuseppe, Ramos-Sevillano, Elisa, Nakajima, Rie, de Assis, Rafael Ramiro, Jasinskas, Algis, Goldblatt, David, Felgner, Philip, Weckbecker, Gisbert, Brown, Jeremy
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876223/
https://ncbi.nlm.nih.gov/pubmed/33584691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.611661
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