A Novel, Multiple-Antigen Pneumococcal Vaccine Protects against Lethal Streptococcus pneumoniae Challenge

Current vaccination against Streptococcus pneumoniae uses vaccines based on capsular polysaccharides from selected serotypes and has led to nonvaccine serotype replacement disease. We have investigated an alternative serotype-independent approach, using multiple-antigen vaccines (MAV) prepared from...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Chan, Win-Yan, Entwisle, Claire, Ercoli, Giuseppe, Ramos-Sevillano, Elise, McIlgorm, Ann, Cecchini, Paola, Bailey, Christopher, Lam, Oliver, Whiting, Gail, Green, Nicola, Goldblatt, David, Wheeler, Jun X., Brown, Jeremy S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386546/
https://ncbi.nlm.nih.gov/pubmed/30530620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00846-18
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