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Antibodies to the Iron Uptake ABC Transporter Lipoproteins PiaA and PiuA Promote Opsonophagocytosis of Streptococcus pneumoniae

PiaA and PiuA are the lipoprotein components of the Pia and Piu Streptococcus pneumoniae iron uptake ABC transporters and are required for full virulence in mouse models of infection. Active or passive vaccination with recombinant PiuA and PiaA protects mice against invasive S. pneumoniae disease. I...

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Bibliografiske detaljer
Main Authors: Jomaa, Maha, Yuste, Jose, Paton, James C., Jones, Christopher, Dougan, Gordon, Brown, Jeremy S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230898/
https://ncbi.nlm.nih.gov/pubmed/16177364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.6852-6859.2005
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