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The pneumococcal iron uptake protein A (PiuA) specifically recognizes tetradentate Fe(III) bis- and mono-catechol complexes

Streptococcus pneumoniae (Spn) is an important Gram-positive human pathogen that causes millions of infections worldwide with an increasing occurrence of antibiotic resistance. Fe acquisition is a crucial virulence determinant in Spn; further, Spn relies on exogenous Fe(III)-siderophore scavenging t...

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Détails bibliographiques
Publié dans:J Mol Biol
Auteurs principaux: Zhang, Yifan, Edmonds, Katherine A., Raines, Daniel J., Murphy, Brennan A., Wu, Hongwei, Guo, Chuchu, Nolan, Elizabeth M., VanNieuwenhze, Michael S., Duhme-Klair, Anne-K., Giedroc, David P.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502554/
https://ncbi.nlm.nih.gov/pubmed/32795535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.08.005
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