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Structure and Function of the PiuA and PirA Siderophore-Drug Receptors from Pseudomonas aeruginosa and Acinetobacter baumannii

The outer membrane of Gram-negative bacteria presents an efficient barrier to the permeation of antimicrobial molecules. One strategy pursued to circumvent this obstacle is to hijack transport systems for essential nutrients, such as iron. BAL30072 and MC-1 are two monobactams conjugated to a dihydr...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Moynié, Lucile, Luscher, Alexandre, Rolo, Dora, Pletzer, Daniel, Tortajada, Antoni, Weingart, Helge, Braun, Yvonne, Page, Malcolm G. P., Naismith, James H., Köhler, Thilo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365723/
https://ncbi.nlm.nih.gov/pubmed/28137795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02531-16
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