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Antibodies to the Iron Uptake ABC Transporter Lipoproteins PiaA and PiuA Promote Opsonophagocytosis of Streptococcus pneumoniae

PiaA and PiuA are the lipoprotein components of the Pia and Piu Streptococcus pneumoniae iron uptake ABC transporters and are required for full virulence in mouse models of infection. Active or passive vaccination with recombinant PiuA and PiaA protects mice against invasive S. pneumoniae disease. I...

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書誌詳細
主要な著者: Jomaa, Maha, Yuste, Jose, Paton, James C., Jones, Christopher, Dougan, Gordon, Brown, Jeremy S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230898/
https://ncbi.nlm.nih.gov/pubmed/16177364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.6852-6859.2005
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