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Lessons, Challenges and Future Therapeutic Opportunities for PI3K Inhibition in CLL

SIMPLE SUMMARY: The phosphoinositide 3-kinase (PI3K) is a family of kinases that play a key role in the biology of chronic lymphocytic leukemia (CLL). Inhibitors of PI3K demonstrated efficacy in the treatment of CLL, associated with significant adverse events that limited the clinical use of this dr...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Guarente, Valerio, Sportoletti, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7999552/
https://ncbi.nlm.nih.gov/pubmed/33805745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061280
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