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Lessons, Challenges and Future Therapeutic Opportunities for PI3K Inhibition in CLL

SIMPLE SUMMARY: The phosphoinositide 3-kinase (PI3K) is a family of kinases that play a key role in the biology of chronic lymphocytic leukemia (CLL). Inhibitors of PI3K demonstrated efficacy in the treatment of CLL, associated with significant adverse events that limited the clinical use of this dr...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Guarente, Valerio, Sportoletti, Paolo
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7999552/
https://ncbi.nlm.nih.gov/pubmed/33805745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061280
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