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Idiosyncratic Drug-Induced Liver Injury: Mechanistic and Clinical Challenges

Idiosyncratic drug-induced liver injury (IDILI) remains a significant problem for patients and drug development. The idiosyncratic nature of IDILI makes mechanistic studies difficult, and little is known of its pathogenesis for certain. Circumstantial evidence suggests that most, but not all, IDILI...

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Опубликовано в: :Int J Mol Sci
Главные авторы: Jee, Alison, Sernoskie, Samantha Christine, Uetrecht, Jack
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998339/
https://ncbi.nlm.nih.gov/pubmed/33799477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062954
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