Idiosyncratic Drug-Induced Liver Injury: Mechanistic and Clinical Challenges

Idiosyncratic drug-induced liver injury (IDILI) remains a significant problem for patients and drug development. The idiosyncratic nature of IDILI makes mechanistic studies difficult, and little is known of its pathogenesis for certain. Circumstantial evidence suggests that most, but not all, IDILI...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Jee, Alison, Sernoskie, Samantha Christine, Uetrecht, Jack
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998339/
https://ncbi.nlm.nih.gov/pubmed/33799477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062954
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