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Mechanistic Studies of Idiosyncratic DILI: Clinical Implications

The idiosyncratic nature of idiosyncratic drug-induced liver injury (IDILI) makes mechanistic studies very difficult, and little is known with certainty. However, the fact that the IDILI caused by some drugs is associated with specific HLA genotypes provides strong evidence that it is mediated by th...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Autor principal: Uetrecht, Jack
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676790/
https://ncbi.nlm.nih.gov/pubmed/31402866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00837
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