Nalaganje...
Novel Antimalarial Tetrazoles and Amides Active Against the Hemoglobin Degradation Pathway in Plasmodium falciparum
Malaria control programs continue to be threatened by drug resistance. To identify new antimalarials we conducted a phenotypic screen and identified a novel tetrazole-based series that shows fast-kill kinetics and a relatively low propensity to develop high-level resistance. Preliminary structure ac...
Shranjeno v:
| izdano v: | J Med Chem |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2021
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7997635/ https://ncbi.nlm.nih.gov/pubmed/33620219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c02022 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|