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An Antiparasitic Compound from the Medicines for Malaria Venture Pathogen Box Promotes Leishmania Tubulin Polymerization

The few frontline antileishmanial drugs are poorly effective and toxic. To search for new drugs for this neglected tropical disease, we tested the activity of compounds in the Medicines for Malaria Venture (MMV) “Pathogen Box” against Leishmania amazonensis axenic amastigotes. Screening yielded six...

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Bibliografische gegevens
Gepubliceerd in:ACS Infect Dis
Hoofdauteurs: Ullah, Imran, Gahalawat, Suraksha, Booshehri, Laela M., Niederstrasser, Hanspeter, Majumdar, Shreoshi, Leija, Christopher, Bradford, James M., Hu, Bin, Ready, Joseph M., Wetzel, Dawn M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8059355/
https://ncbi.nlm.nih.gov/pubmed/32686409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00122
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