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An Antiparasitic Compound from the Medicines for Malaria Venture Pathogen Box Promotes Leishmania Tubulin Polymerization

The few frontline antileishmanial drugs are poorly effective and toxic. To search for new drugs for this neglected tropical disease, we tested the activity of compounds in the Medicines for Malaria Venture (MMV) “Pathogen Box” against Leishmania amazonensis axenic amastigotes. Screening yielded six...

詳細記述

保存先:
書誌詳細
出版年:ACS Infect Dis
主要な著者: Ullah, Imran, Gahalawat, Suraksha, Booshehri, Laela M., Niederstrasser, Hanspeter, Majumdar, Shreoshi, Leija, Christopher, Bradford, James M., Hu, Bin, Ready, Joseph M., Wetzel, Dawn M.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8059355/
https://ncbi.nlm.nih.gov/pubmed/32686409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00122
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