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An Antiparasitic Compound from the Medicines for Malaria Venture Pathogen Box Promotes Leishmania Tubulin Polymerization

The few frontline antileishmanial drugs are poorly effective and toxic. To search for new drugs for this neglected tropical disease, we tested the activity of compounds in the Medicines for Malaria Venture (MMV) “Pathogen Box” against Leishmania amazonensis axenic amastigotes. Screening yielded six...

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Vydáno v:ACS Infect Dis
Hlavní autoři: Ullah, Imran, Gahalawat, Suraksha, Booshehri, Laela M., Niederstrasser, Hanspeter, Majumdar, Shreoshi, Leija, Christopher, Bradford, James M., Hu, Bin, Ready, Joseph M., Wetzel, Dawn M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8059355/
https://ncbi.nlm.nih.gov/pubmed/32686409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00122
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