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An Antiparasitic Compound from the Medicines for Malaria Venture Pathogen Box Promotes Leishmania Tubulin Polymerization

The few frontline antileishmanial drugs are poorly effective and toxic. To search for new drugs for this neglected tropical disease, we tested the activity of compounds in the Medicines for Malaria Venture (MMV) “Pathogen Box” against Leishmania amazonensis axenic amastigotes. Screening yielded six...

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Dettagli Bibliografici
Pubblicato in:ACS Infect Dis
Autori principali: Ullah, Imran, Gahalawat, Suraksha, Booshehri, Laela M., Niederstrasser, Hanspeter, Majumdar, Shreoshi, Leija, Christopher, Bradford, James M., Hu, Bin, Ready, Joseph M., Wetzel, Dawn M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8059355/
https://ncbi.nlm.nih.gov/pubmed/32686409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00122
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