p62/SQSTM1/Keap1/NRF2 Axis Reduces Cancer Cells Death-Sensitivity in Response to Zn(II)–Curcumin Complex

The hyperactivation of nuclear factor erythroid 2 p45-related factor 2 (NRF2), frequently found in many tumor types, can be responsible for cancer resistance to therapies and poor patient prognosis. Curcumin has been shown to activate NRF2 that has cytotprotective or protumorigenic roles according t...

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Detalles Bibliográficos
Publicado en:Biomolecules
Autores principales: Garufi, Alessia, Giorno, Eugenia, Gilardini Montani, Maria Saveria, Pistritto, Giuseppa, Crispini, Alessandra, Cirone, Mara, D’Orazi, Gabriella
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7996602/
https://ncbi.nlm.nih.gov/pubmed/33669070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11030348
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