A ruthenium(II)-curcumin compound modulates NRF2 expression balancing the cancer cell death/survival outcome according to p53 status

ABSTRACT: BACKGROUND: Tumor progression and tumor response to anticancer therapies may be affected by activation of oncogenic pathways such as the antioxidant one induced by NRF2 (nuclear factor erythroid 2-related factor 2) transcription factor and the pathways modified by deregulation of oncosuppr...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Garufi, Alessia, Baldari, Silvia, Pettinari, Riccardo, Gilardini Montani, Maria Saveria, D’Orazi, Valerio, Pistritto, Giuseppa, Crispini, Alessandra, Giorno, Eugenia, Toietta, Gabriele, Marchetti, Fabio, Cirone, Mara, D’Orazi, Gabriella
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325274/
https://ncbi.nlm.nih.gov/pubmed/32605658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01628-5
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