Cytotoxic Drugs Activate KSHV Lytic Cycle in Latently Infected PEL Cells by Inducing a Moderate ROS Increase Controlled by HSF1, NRF2 and p62/SQSTM1

Previous studies have indicated that cytotoxic treatments may induce or not activate viral lytic cycle activation in cancer cells latently infected by Kaposi’s sarcoma-associated herpesvirus (KSHV). To investigate the molecular mechanisms responsible for such an effect, we compared two cytotoxic tre...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Granato, Marisa, Gilardini Montani, Maria Saveria, Angiolillo, Camilla, D’Orazi, Gabriella, Faggioni, Alberto, Cirone, Mara
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356381/
https://ncbi.nlm.nih.gov/pubmed/30586869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11010008
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