The activation of KSHV lytic cycle blocks autophagy in PEL cells

This study confirms that autophagy is activated concomitantly with KSHV lytic cycle induction, and that autophagy inhibition by BECN1 knockdown reduces viral lytic gene expression. In addition, we extend previous observations and show that autophagy is blocked at late steps, during viral replication...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Granato, Marisa, Santarelli, Roberta, Filardi, Mariarosaria, Gonnella, Roberta, Farina, Antonella, Torrisi, Maria Rosaria, Faggioni, Alberto, Cirone, Mara
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Basic Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824593/
https://ncbi.nlm.nih.gov/pubmed/26391343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1091911
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