Kaposi sarcoma associated herpesvirus (KSHV) induces AKT hyperphosphorylation, bortezomib-resistance and GLUT-1 plasma membrane exposure in THP-1 monocytic cell line

BACKGROUND: Phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling pathway regulates multiple cellular processes such as cell proliferation, evasion from apoptosis, migration, glucose metabolism, protein synthesis and proper differentiation in immune cells. Kaposi sa...

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Detalhes bibliográficos
Main Authors: Gonnella, Roberta, Santarelli, Roberta, Farina, Antonella, Granato, Marisa, D’Orazi, Gabriella, Faggioni, Alberto, Cirone, Mara
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874756/
https://ncbi.nlm.nih.gov/pubmed/24422998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-32-79
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