Kaposi sarcoma associated herpesvirus (KSHV) induces AKT hyperphosphorylation, bortezomib-resistance and GLUT-1 plasma membrane exposure in THP-1 monocytic cell line

BACKGROUND: Phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling pathway regulates multiple cellular processes such as cell proliferation, evasion from apoptosis, migration, glucose metabolism, protein synthesis and proper differentiation in immune cells. Kaposi sa...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gonnella, Roberta, Santarelli, Roberta, Farina, Antonella, Granato, Marisa, D’Orazi, Gabriella, Faggioni, Alberto, Cirone, Mara
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2013
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874756/
https://ncbi.nlm.nih.gov/pubmed/24422998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-32-79
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