Kaposi sarcoma associated herpesvirus (KSHV) induces AKT hyperphosphorylation, bortezomib-resistance and GLUT-1 plasma membrane exposure in THP-1 monocytic cell line

BACKGROUND: Phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling pathway regulates multiple cellular processes such as cell proliferation, evasion from apoptosis, migration, glucose metabolism, protein synthesis and proper differentiation in immune cells. Kaposi sa...

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Bibliografiska uppgifter
Huvudupphovsmän: Gonnella, Roberta, Santarelli, Roberta, Farina, Antonella, Granato, Marisa, D’Orazi, Gabriella, Faggioni, Alberto, Cirone, Mara
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874756/
https://ncbi.nlm.nih.gov/pubmed/24422998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-32-79
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