The activation of KSHV lytic cycle blocks autophagy in PEL cells

This study confirms that autophagy is activated concomitantly with KSHV lytic cycle induction, and that autophagy inhibition by BECN1 knockdown reduces viral lytic gene expression. In addition, we extend previous observations and show that autophagy is blocked at late steps, during viral replication...

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Bibliografski detalji
Izdano u:Autophagy
Glavni autori: Granato, Marisa, Santarelli, Roberta, Filardi, Mariarosaria, Gonnella, Roberta, Farina, Antonella, Torrisi, Maria Rosaria, Faggioni, Alberto, Cirone, Mara
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Basic Brief Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824593/
https://ncbi.nlm.nih.gov/pubmed/26391343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1091911
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