The activation of KSHV lytic cycle blocks autophagy in PEL cells

This study confirms that autophagy is activated concomitantly with KSHV lytic cycle induction, and that autophagy inhibition by BECN1 knockdown reduces viral lytic gene expression. In addition, we extend previous observations and show that autophagy is blocked at late steps, during viral replication...

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Publicat a:Autophagy
Autors principals: Granato, Marisa, Santarelli, Roberta, Filardi, Mariarosaria, Gonnella, Roberta, Farina, Antonella, Torrisi, Maria Rosaria, Faggioni, Alberto, Cirone, Mara
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Basic Brief Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824593/
https://ncbi.nlm.nih.gov/pubmed/26391343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1091911
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